Chagas disease is a silent disease that is caused by Trypanosoma Cruzi, a parasite found in the Triatomine bug known as the kissing bug. It has that name due to its habit of biting faces at night. When they bite someone, they can suck blood for 10 to 20 minutes, fill up so much that their bodies look like a balloon, and their saliva also secretes allergens and irritants that cause swelling at the bite site. The transmission occurs when the bug gets full, it poops at the bite site, and they carry live parasites that, when they enter the broken, pierced skin by scratching the site, they quickly enter the bloodstream. They can stop at some point, enter the cell, reproduce, burst out of that cell, travel again into the bloodstream, and nest in the heart muscle, their favorite place because of the large quantity of blood available, and there they can live for years, causing dilated cardiomyopathy, which reduces the heart's ability to pump blood.
Trypanosoma Cruzi was detected 9 thousand years ago in mummies in the Atacama Desert.
In 1909, Carlos Chagas, a Brazilian physician, scientist, microbiologist, and clinician researcher, after examining two year two-year-old little girl with fever, swollen lymph nodes, and enlarged spleen and liver, collected her blood and detected Trypanosomes identical to the ones in Triatomine bugs, "kissing bugs" that's why it was named after his last name, Chagas Disease.
As of now, there are no vaccines for Chagas disease, despite mice infected with Chagas disease having been treated with experimental vaccines; no humans have participated in trials yet.
Treatment is available only efficiently during the acute phase, as of 2018 standard treatment for acute stage of Chagas disease is: benznidazole dose given 3 times a day for 60 to 90 days, with less side effects, and niturtimox, this last drug has more side effects reports, both drugs are provided by the CDC, thats why it is importnat to contact CDC for the infection and control.
Signs and symptoms. Acute phase: as soon as bitten by the kissing bug, it appears a swollen site and this is probably the most accurate sign; symptoms may or may not occur, which include headache, flu-like symptoms. Chronic phase, after 4 to 8 weeks after the bite, the Chagas disease develops, better saying the Trypanosome Cruzi chooses a place to reside, which can be in any organ, it takes years to cause damage. The heart is their favorite place to live. long-term symptoms are shortness of breath, chest pain, heart palpitations, fainting, arrhythmias, dilated cardiomyopathy, and heart failure. Most people don't even know they have Chagas disease until they feel so sick.
Ways of transmission by the bite of the kissing bug are by blood transfusions ( Trypanosoma cruzi survives in refrigerated, frozen, and thawed blood), Organ donation, and vertical transmission, mother to baby during pregnancy. Other ways are oral contamination by fruit juices or contaminated food with these bugs.
Ways to avoid the kissing bug are living in well-built houses with no holes, cracks, applying screens on doors and windows, washing food well, and looking carefully if there are bugs in it. If the house is a log, barn, wood, or clay built with visible cracks, use a net over the bed during sleep. Insecticide spray is effective too.
How to test for Chagas? There are blood tests, ELISA or PCR, being more accurate and easier than the traditional Microscopy lab studies, the Machado Guerreiro test, EKG, imaging, such as X-ray, and other ways to detect Chagas disease. It usually takes 10 to 20 years to detect any damage.
Trypanosoma Cruzi in blood smear:
Kissing bugs:
Net over bed: